ARPA-H Funds Two Cancer“ Manhattan Projects”

The Advanced Research Projects Agency for Health (ARPA-H) has launched two major cancer research initiatives, providing tens of millions of dollars in funding to revolutionize treatment. Unlike traditional NIH grants, these large-scale projects bring together top experts, resembling national security efforts like the Manhattan Project. One project, led by Rice University and MD Anderson Cancer Center, received $45 million to develop an implantable device that monitors cancer and adjusts immunotherapy doses in real time—an approach inspired by diabetes management.

Meanwhile, Emory University secured $24.8 million to enhance immune responses using mRNA-encoded antigens and gene modulation technology. With over $240 million already invested in cancer research, ARPA-H’s innovative funding model is shaping the future of oncology.